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Did you mean match and prostate (6,807 results)?
The germline mutational landscape of genitourinary cancers and its indication for prognosis and risk.
Yang Y, Zhang G, Hu C, Luo W, Jiang H, Liu S, Yang H. Yang Y, et al. BMC Urol. 2022 Nov 30;22(1):196. doi: 10.1186/s12894-022-01141-1. BMC Urol. 2022. PMID: 36451132 Free PMC article.
The subset of data of 206 genitourinary cancer patients containing bladder urothelial carcinoma (BLCA), kidney chromophobe carcinoma (KICH), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP) and prostate adenocarcinoma (PRAD) cancer wit …
The subset of data of 206 genitourinary cancer patients containing bladder urothelial carcinoma (BLCA), kidney chromophobe carcinoma (KICH), …
Increased Risk of Hereditary Prostate Cancer in Italian Families with Hereditary Breast and Ovarian Cancer Syndrome Harboring Mutations in BRCA and in Other Susceptibility Genes.
D'Elia G, Caliendo G, Tzioni MM, Albanese L, Passariello L, Molinari AM, Vietri MT. D'Elia G, et al. Genes (Basel). 2022 Sep 21;13(10):1692. doi: 10.3390/genes13101692. Genes (Basel). 2022. PMID: 36292577 Free PMC article.
Hereditary prostate cancer (HPCa) has the highest heritability of any cancer in men. ...This was undertaken in 180 HBOC families, which included 217 males with prostate cancer (PCa). Mutational analysis was further extended to 104 family members of mutated patients. …
Hereditary prostate cancer (HPCa) has the highest heritability of any cancer in men. ...This was undertaken in 180 HBOC families, whi …
Hereditary forms of colorectal cancer.
Castells A. Castells A. Gastroenterol Hepatol. 2016 Sep;39 Suppl 1:62-67. doi: 10.1016/S0210-5705(16)30176-5. Gastroenterol Hepatol. 2016. PMID: 27888866 Review. English, Spanish.
Colorectal cancer is one of the most frequent neoplasms in western countries; it is the third most common cancer in men after prostate and lung cancer and the second most common in women after breast cancer. ...The present article reviews the most novel findings presented …
Colorectal cancer is one of the most frequent neoplasms in western countries; it is the third most common cancer in men after prostate …
Germline DNA Repair Genes Pathogenic Variants Among Mexican Patients With Prostate Cancer.
Chávarri-Guerra Y, Bourlon MT, Rodríguez-Olivares JL, Orozco L, Bazua D, Rodríguez-Faure A, Alcalde-Castro MJ, Castro E, Castillo D, Herzog J, Weitzel J. Chávarri-Guerra Y, et al. Clin Genitourin Cancer. 2023 Oct;21(5):569-573. doi: 10.1016/j.clgc.2023.05.012. Epub 2023 May 23. Clin Genitourin Cancer. 2023. PMID: 37380563
CONCLUSION: Our results showed a low prevalence of known prostate cancer associated PVs and no BRCA PVs in Mexican men with prostate cancer. This suggests that the genetic and/or epidemiologic risk factors for prostate cancer are not well characterized in thi …
CONCLUSION: Our results showed a low prevalence of known prostate cancer associated PVs and no BRCA PVs in Mexican men with prosta …
Whole exome germline sequencing in early-onset prostate cancer patients: Genomic findings and clinical outcomes.
Siegelmann-Danieli N, Neiman V, Bareket-Samish A, Berger R, Peretz A, Alapi H, Tsur E, Patalon T, Beller D, Rimler G, Chodick G, Shohat M. Siegelmann-Danieli N, et al. Prostate. 2024 Jan;84(1):39-46. doi: 10.1002/pros.24622. Epub 2023 Oct 16. Prostate. 2024. PMID: 37842866
We assessed the occurrence of germline likely pathogenic/pathogenic (LP/P) variants, disease features, and clinical outcomes in early-onset prostate cancer. METHODS: This retrospective study (N = 134) included consecutive prostate cancer patients who donated blood s …
We assessed the occurrence of germline likely pathogenic/pathogenic (LP/P) variants, disease features, and clinical outcomes in early-onset …
Genetic variation in DNA repair genes and prostate cancer risk: results from a population-based study.
Agalliu I, Kwon EM, Salinas CA, Koopmeiners JS, Ostrander EA, Stanford JL. Agalliu I, et al. Cancer Causes Control. 2010 Feb;21(2):289-300. doi: 10.1007/s10552-009-9461-5. Epub 2009 Nov 10. Cancer Causes Control. 2010. PMID: 19902366 Free PMC article.
An increase in oxidative DNA damage or decrease in DNA repair capacity with aging or due to germline genetic variation may affect prostate cancer risk. METHODS: Pooled data from two population-based studies (1,457 cases and 1,351 controls) were analyzed to examine associat …
An increase in oxidative DNA damage or decrease in DNA repair capacity with aging or due to germline genetic variation may affect prostat …
Ethnic disparities among men with prostate cancer undergoing germline testing.
Kwon DH, Borno HT, Cheng HH, Zhou AY, Small EJ. Kwon DH, et al. Urol Oncol. 2020 Mar;38(3):80.e1-80.e7. doi: 10.1016/j.urolonc.2019.09.010. Epub 2019 Oct 17. Urol Oncol. 2020. PMID: 31630993
One-hundred eighty-seven men (13.8%) carried a P/LP variant, and the most prevalent P/LP variants were in BRCA2 (3.4%), CHEK2 (2.8%), MUTYH (1.8%), and ATM (1.7%). Age at diagnosis, ethnicity, type of family member with prostate cancer, and type of second cancer wer …
One-hundred eighty-seven men (13.8%) carried a P/LP variant, and the most prevalent P/LP variants were in BRCA2 (3.4%), CHEK2 (2.8%), MUT …
Uncommon variants detected via hereditary cancer panel and suggestions for genetic counseling.
Özdemir Z, Çevik E, Öksüzoğlu ÖBÇ, Doğan M, Ateş Ö, Esin E, Bilgetekin İ, Demirci U, Köseoğlu Ç, Topal A, Karadurmuş N, Erdem HB, Bahsi T. Özdemir Z, et al. Mutat Res. 2023 Jul-Dec;827:111831. doi: 10.1016/j.mrfmmm.2023.111831. Epub 2023 Jul 4. Mutat Res. 2023. PMID: 37453313
After excluding the 46 BRCA1/2-positive patients, among the remaining 126 patients; there were 60 (4.8%) breast cancer, 33 (2.6%) colorectal cancer, 9 (0.7%) ovarian cancer, 5 (0.4%) endometrium cancer, 5 (0.4%) stomach cancer, 3 (0.2%) prostate cancer patients. The most a …
After excluding the 46 BRCA1/2-positive patients, among the remaining 126 patients; there were 60 (4.8%) breast cancer, 33 (2.6%) colorectal …
Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.
Win AK, Reece JC, Dowty JG, Buchanan DD, Clendenning M, Rosty C, Southey MC, Young JP, Cleary SP, Kim H, Cotterchio M, Macrae FA, Tucker KM, Baron JA, Burnett T, Le Marchand L, Casey G, Haile RW, Newcomb PA, Thibodeau SN, Hopper JL, Gallinger S, Winship IM, Lindor NM, Jenkins MA. Win AK, et al. Int J Cancer. 2016 Oct 1;139(7):1557-63. doi: 10.1002/ijc.30197. Epub 2016 Jun 2. Int J Cancer. 2016. PMID: 27194394 Free PMC article.
Germline mutations in the DNA base excision repair gene MUTYH are known to increase a carrier's risk of colorectal cancer. However, the risks of other (extracolonic) cancers for MUTYH mutation carriers are not well defined. We identified 266 probands (91% Caucasians …
Germline mutations in the DNA base excision repair gene MUTYH are known to increase a carrier's risk of colorectal cancer. However, t …
Reduced expression of the DNA glycosylase gene MUTYH is associated with an increased number of somatic mutations via a reduction in the DNA repair capacity in prostate adenocarcinoma.
Shinmura K, Kato H, Kawanishi Y, Yoshimura K, Igarashi H, Goto M, Tao H, Inoue Y, Sugiyama T, Furuse H, Ozono S, Sugimura H. Shinmura K, et al. Mol Carcinog. 2017 Feb;56(2):781-788. doi: 10.1002/mc.22509. Epub 2016 Jun 10. Mol Carcinog. 2017. PMID: 27253753
To determine the reason why reduced MUTYH expression leads to somatic mutation loads in prostate adenocarcinoma, we compared the DNA repair capacities between PC-3 prostatic cell line derived clones with different MUTYH expression levels. Both the capa …
To determine the reason why reduced MUTYH expression leads to somatic mutation loads in prostate adenocarcinoma, we compared t …
19 results